Tranmere boss Micky Mellon will be keen to move on from their FA Cup thrashing at the hands of Manchester United as Sky Bet League One rivals Sunderland visit Prenton Park.
Rovers were beaten 6-0 on Sunday, with Mellon now turning his attention back to the fight to stave off relegation.
Paul Mullin may be available to start having only been deemed fit enough for a substitute’s role on Sunday, while Ollie Banks is still missing with a quad injury.
Defenders Mark Ellis and Evan Gumbs are also likely to remain absent for 21st-placed Tranmere.
Promotion-chasing Sunderland make the trip having seen a three-match winning streak ended by a goalless draw at home to Doncaster on Friday night.
The Black Cats will be bolstered by the signing of midfielder Josh Scowen from QPR, with manager Phil Parkinson able to use his new recruit straight away.
Bailey Wright is also pushing for his first involvement since joining on loan from Bristol City earlier in the window.
But Elliot Embleton (hamstring) is out after suffering a fresh injury setback last week.