Exeter manager Matty Taylor expects to again see his squad stretched for the Sky Bet League Two match against Cheltenham.
The Grecians could be without as many as 10 players, so Taylor has recalled defender Alex Hartridge and midfielder Joel Randall from their loan spells as cover.
Jake Taylor remains suspended, with the midfielder in the middle of a three-match ban following his red card in the defeat at Bradford.
Striker Nicky Ajose is closing in on a return to action following an operation on a knee problem which has sidelined him since early September.
Cheltenham boss Michael Duff is expecting a response following the 7-4 home defeat against Newport in the Leasing.com Trophy, which saw them knocked out at the group stage.
Forward Reuben Reid came off the bench for a belated debut following a summer move from Forest Green, but his return from a knee problem will be carefully managed.
On loan Hull midfielder Max Sheaf marked his return to the starting XI after a hamstring injury with a goal, so should be involved in the squad again.
Duff reported no other fresh injury concerns, with Tahvon Campbell (knee) and defender Josh Debayo (groin) both still sidelined.