Hull could have Matthew Pennington and Stephen Kingsley back in contention against Yorkshire rivals Sheffield Wednesday.
The defenders missed the 2-2 draw with Cardiff on Saturday through injury, but Tigers boss Grant McCann is hopeful the duo will return on Tuesday night.
Callum Elder (calf) was also absent against the Bluebirds and he is set to miss out again, although there is a chance he could be involved against Huddersfield at the weekend.
Jon Toral is also unlikely to feature having missed the Tigers’ last three matches with the hamstring strain he sustained against Millwall at the end of August.
Garry Monk will want to continue his unbeaten start as Sheffield Wednesday manager at the KCOM Stadium.
However, the Owls, who have taken seven points from Monk’s first three league games in charge, are waiting on the fitness of midfielder Sam Hutchinson.
Hutchinson, who remains a yellow card away from a suspension, was substituted just before half-time in the emphatic 4-1 win at Middlesbrough on Saturday after suffering a knock to his knee.
There may be a return to action for skipper Tom Lees after a hamstring injury, but Joe Wildsmith remains a long-term absentee.