Carlisle manager Steven Pressley has received mixed news on the injury front ahead of the visit of Cambridge.
Macaulay Gillesphey could be available for selection in two weeks’ time as he returns from knee surgery.
But fellow defender Peter Grant is a fresh doubt after failing to complete training on Wednesday.
If Grant is ruled out, 16-year-old Jarrad Branthwaite could remain in the first-team picture after being on the bench for the first time in last week’s draw at Forest Green.
Cambridge head coach Colin Calderwood will be without the services of Reggie Lambe and Jake Doyle-Hayes for the game at Brunton Park.
Both players are away on international duty, with Lambe’s Bermuda taking on the Dominican Republic.
Fellow midfielder Doyle-Hayes is part of the Republic of Ireland’s under-21 squad for their European Championship qualifier against Luxembourg.
Defender Brad Halliday would have missed last week’s postponed game at Bury through injury but has returned to training and is set to be available on Saturday.