Peterhead will be without Jack Leitch for the next six weeks.
Blue Toon boss Jim McInally revealed the midfielder tore ankle ligaments at training earlier this week.
The 24-year-old rolled his ankle on Tuesday while training.
It quickly became swollen and now the Buchan team have discovered Leitch has torn ligaments which will keep him out for a number of weeks.
Balmoor gaffer McInally admits it is a big blow to have the former Motherwell and Airdrieonians player on the sidelines when he has featured in every game so far this season.
He said: “Jack looks like he will be out for six weeks after he went over his ankle. He rolled it at training and it was like a balloon when he left.
“After that we discovered he’s torn the ligaments. It’s a big blow to us that he will be out for that length of time.
“We have the bodies to deal with it and it might give Ryan Conroy a chance to start.”
Leitch is not the only injury concern McInally has ahead of Clyde’s visit to Balmoor on Saturday.
Cammy Eadie is out with a medial ligament problem and fellow defender Scott Hooper is still getting over an ankle problem.
Centre-back Mick Dunlop and influential central midfielder Simon Ferry have also sustained knocks.
McInally added: “Cammy will be out for a couple of weeks. Scott has trained, but he’s still not pain free.
“He could get away with playing, but he doesn’t want to take the risk.
“Mick also has a wee knock so we’ll wait and see how he is. Simon went over his ankle, but he trained and doesn’t think it should be a problem.”