Dons boss Derek McInnes has revealed that freshening up his team was important for the start of the domestic season.
Aberdeen started their Premiership campaign with a 2-0 win at home to Hamilton on Sunday.
The Reds travel to Lanarkshire tomorrow to face the same opposition in the last 16 of the Betfred Cup.
After losing to Apollon Limassol in the heat of Cyprus in the Europa League third qualifying round on Thursday, McInnes made four changes to his starting 11 in a bid to keep the team fresh.
Mark Reynolds, Greg Stewart, Gary Mackay-Steven and Jayden Stockley all dropped out of the side that started in Larnaca.
Kari Arnason came in for his first competitive appearance of his second spell in red.
Scott Wright, Greg Tansey and Nicky Maynard also started.
McInnes revealed he had learned from their opening day experience of three years ago.
After facing Real Sociedad in the Europa League third qualifying round on the Thursday, McInnes only made two changes to his team for the league opener on Sunday against Dundee United.
The consequence was that a tired Dons team were picked off on the counter-attack by United and beaten 3-0.
Recalling that experience, McInnes said it made him aware he needed to freshen up his side for the Premiership opener against Accies.
He said: “I thought it was important to freshen up the team.
“Just from the benefit of having experienced that over the last few years.
“I remember the one time we didn’t do it and we lost against Dundee United when they did us on the counter-attack a couple of times and I was kicking myself that I never freshened the team up enough.
“The freshness helped the team get a result, but it wasn’t just the freshness it was the other ones that had to go in again, and I thought some of the performances were more than decent.
“Given the exertions of Thursday and Friday, to get them up and ready for the opening game was important.”
With Wednesday’s match at the Superseal Stadium being Aberdeen’s third in a week, McInnes may change his team again in an attempt to ensure his side produces a similarly dominant performance against Hamilton.
One change he may make is to bring Adam Rooney back into the team.
The striker sat out both legs of the European tie with Limassol and also missed Sunday’s game against Martin Canning’s team with a thigh strain.
However, he was expected to return to full training today and McInnes said he may play tomorrow evening.
He added: “He was touch and go for Sunday and will be the same for Wednesday, but it would be great to have him back.”